WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_V$E2F_Q4       ID:DB_ID:2092
C=231; O=13; E=0.48; R=26.97; rawP=2.43e-15; adjP=1.20e-13
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000093009 NA CDC45 cell division cycle 45 homolog (S. cerevisiae) 8318 ENSG00000093009
2  ENSG00000198826 NA ARHGAP11A Rho GTPase activating protein 11A 9824 ENSG00000198826
3  ENSG00000166803 NA KIAA0101 KIAA0101 9768 ENSG00000166803
4  ENSG00000100479 NA POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 5427 ENSG00000100479
5  ENSG00000051180 NA RAD51 RAD51 homolog (S. cerevisiae) 5888 ENSG00000051180
6  ENSG00000167513 NA CDT1 chromatin licensing and DNA replication factor 1 81620 ENSG00000167513
7  ENSG00000101412 NA E2F1 E2F transcription factor 1 1869 ENSG00000101412
8  ENSG00000175643 NA RMI2 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 116028 ENSG00000175643
9  ENSG00000171848 NA RRM2 ribonucleotide reductase M2 6241 ENSG00000171848
10  ENSG00000094804 NA CDC6 cell division cycle 6 homolog (S. cerevisiae) 990 ENSG00000094804
11  ENSG00000127564 NA PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 9088 ENSG00000127564
12  ENSG00000170312 NA CDK1 cyclin-dependent kinase 1 983 ENSG00000170312
13  ENSG00000106462 NA EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 ENSG00000106462


Database:Transcription Target       Name:hsa_V$E2F_Q6       ID:DB_ID:2094
C=229; O=13; E=0.48; R=27.20; rawP=2.17e-15; adjP=1.20e-13
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000093009 NA CDC45 cell division cycle 45 homolog (S. cerevisiae) 8318 ENSG00000093009
2  ENSG00000198826 NA ARHGAP11A Rho GTPase activating protein 11A 9824 ENSG00000198826
3  ENSG00000166803 NA KIAA0101 KIAA0101 9768 ENSG00000166803
4  ENSG00000100479 NA POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 5427 ENSG00000100479
5  ENSG00000051180 NA RAD51 RAD51 homolog (S. cerevisiae) 5888 ENSG00000051180
6  ENSG00000167513 NA CDT1 chromatin licensing and DNA replication factor 1 81620 ENSG00000167513
7  ENSG00000101412 NA E2F1 E2F transcription factor 1 1869 ENSG00000101412
8  ENSG00000175643 NA RMI2 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 116028 ENSG00000175643
9  ENSG00000171848 NA RRM2 ribonucleotide reductase M2 6241 ENSG00000171848
10  ENSG00000094804 NA CDC6 cell division cycle 6 homolog (S. cerevisiae) 990 ENSG00000094804
11  ENSG00000127564 NA PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 9088 ENSG00000127564
12  ENSG00000170312 NA CDK1 cyclin-dependent kinase 1 983 ENSG00000170312
13  ENSG00000106462 NA EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 ENSG00000106462


Database:Transcription Target       Name:hsa_V$E2F1_Q6       ID:DB_ID:2097
C=228; O=12; E=0.48; R=25.22; rawP=6.79e-14; adjP=1.68e-12
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198826 NA ARHGAP11A Rho GTPase activating protein 11A 9824 ENSG00000198826
2  ENSG00000166803 NA KIAA0101 KIAA0101 9768 ENSG00000166803
3  ENSG00000100479 NA POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 5427 ENSG00000100479
4  ENSG00000167513 NA CDT1 chromatin licensing and DNA replication factor 1 81620 ENSG00000167513
5  ENSG00000101412 NA E2F1 E2F transcription factor 1 1869 ENSG00000101412
6  ENSG00000175643 NA RMI2 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 116028 ENSG00000175643
7  ENSG00000106367 NA AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1174 ENSG00000106367
8  ENSG00000171848 NA RRM2 ribonucleotide reductase M2 6241 ENSG00000171848
9  ENSG00000094804 NA CDC6 cell division cycle 6 homolog (S. cerevisiae) 990 ENSG00000094804
10  ENSG00000127564 NA PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 9088 ENSG00000127564
11  ENSG00000170312 NA CDK1 cyclin-dependent kinase 1 983 ENSG00000170312
12  ENSG00000106462 NA EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 ENSG00000106462


Database:Transcription Target       Name:hsa_V$E2F1DP1RB_01       ID:DB_ID:2235
C=228; O=12; E=0.48; R=25.22; rawP=6.79e-14; adjP=1.68e-12
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198826 NA ARHGAP11A Rho GTPase activating protein 11A 9824 ENSG00000198826
2  ENSG00000166803 NA KIAA0101 KIAA0101 9768 ENSG00000166803
3  ENSG00000100479 NA POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 5427 ENSG00000100479
4  ENSG00000051180 NA RAD51 RAD51 homolog (S. cerevisiae) 5888 ENSG00000051180
5  ENSG00000167513 NA CDT1 chromatin licensing and DNA replication factor 1 81620 ENSG00000167513
6  ENSG00000101412 NA E2F1 E2F transcription factor 1 1869 ENSG00000101412
7  ENSG00000175643 NA RMI2 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 116028 ENSG00000175643
8  ENSG00000171848 NA RRM2 ribonucleotide reductase M2 6241 ENSG00000171848
9  ENSG00000094804 NA CDC6 cell division cycle 6 homolog (S. cerevisiae) 990 ENSG00000094804
10  ENSG00000127564 NA PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 9088 ENSG00000127564
11  ENSG00000170312 NA CDK1 cyclin-dependent kinase 1 983 ENSG00000170312
12  ENSG00000106462 NA EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 ENSG00000106462


Database:Transcription Target       Name:hsa_V$E2F1DP1_01       ID:DB_ID:2231
C=231; O=11; E=0.48; R=22.82; rawP=2.35e-12; adjP=2.91e-11
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198826 NA ARHGAP11A Rho GTPase activating protein 11A 9824 ENSG00000198826
2  ENSG00000166803 NA KIAA0101 KIAA0101 9768 ENSG00000166803
3  ENSG00000100479 NA POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 5427 ENSG00000100479
4  ENSG00000101412 NA E2F1 E2F transcription factor 1 1869 ENSG00000101412
5  ENSG00000175643 NA RMI2 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 116028 ENSG00000175643
6  ENSG00000106367 NA AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1174 ENSG00000106367
7  ENSG00000171848 NA RRM2 ribonucleotide reductase M2 6241 ENSG00000171848
8  ENSG00000094804 NA CDC6 cell division cycle 6 homolog (S. cerevisiae) 990 ENSG00000094804
9  ENSG00000127564 NA PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 9088 ENSG00000127564
10  ENSG00000170312 NA CDK1 cyclin-dependent kinase 1 983 ENSG00000170312
11  ENSG00000106462 NA EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 ENSG00000106462


Database:Transcription Target       Name:hsa_V$E2F1DP2_01       ID:DB_ID:2232
C=231; O=11; E=0.48; R=22.82; rawP=2.35e-12; adjP=2.91e-11
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198826 NA ARHGAP11A Rho GTPase activating protein 11A 9824 ENSG00000198826
2  ENSG00000166803 NA KIAA0101 KIAA0101 9768 ENSG00000166803
3  ENSG00000100479 NA POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 5427 ENSG00000100479
4  ENSG00000101412 NA E2F1 E2F transcription factor 1 1869 ENSG00000101412
5  ENSG00000175643 NA RMI2 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 116028 ENSG00000175643
6  ENSG00000106367 NA AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1174 ENSG00000106367
7  ENSG00000171848 NA RRM2 ribonucleotide reductase M2 6241 ENSG00000171848
8  ENSG00000094804 NA CDC6 cell division cycle 6 homolog (S. cerevisiae) 990 ENSG00000094804
9  ENSG00000127564 NA PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 9088 ENSG00000127564
10  ENSG00000170312 NA CDK1 cyclin-dependent kinase 1 983 ENSG00000170312
11  ENSG00000106462 NA EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 ENSG00000106462


Database:Transcription Target       Name:hsa_V$E2F_02       ID:DB_ID:1870
C=231; O=11; E=0.48; R=22.82; rawP=2.35e-12; adjP=2.91e-11
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198826 NA ARHGAP11A Rho GTPase activating protein 11A 9824 ENSG00000198826
2  ENSG00000166803 NA KIAA0101 KIAA0101 9768 ENSG00000166803
3  ENSG00000100479 NA POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 5427 ENSG00000100479
4  ENSG00000101412 NA E2F1 E2F transcription factor 1 1869 ENSG00000101412
5  ENSG00000175643 NA RMI2 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 116028 ENSG00000175643
6  ENSG00000106367 NA AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1174 ENSG00000106367
7  ENSG00000171848 NA RRM2 ribonucleotide reductase M2 6241 ENSG00000171848
8  ENSG00000094804 NA CDC6 cell division cycle 6 homolog (S. cerevisiae) 990 ENSG00000094804
9  ENSG00000127564 NA PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 9088 ENSG00000127564
10  ENSG00000170312 NA CDK1 cyclin-dependent kinase 1 983 ENSG00000170312
11  ENSG00000106462 NA EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 ENSG00000106462


Database:Transcription Target       Name:hsa_V$E2F4DP2_01       ID:DB_ID:2234
C=231; O=11; E=0.48; R=22.82; rawP=2.35e-12; adjP=2.91e-11
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198826 NA ARHGAP11A Rho GTPase activating protein 11A 9824 ENSG00000198826
2  ENSG00000166803 NA KIAA0101 KIAA0101 9768 ENSG00000166803
3  ENSG00000100479 NA POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 5427 ENSG00000100479
4  ENSG00000101412 NA E2F1 E2F transcription factor 1 1869 ENSG00000101412
5  ENSG00000175643 NA RMI2 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 116028 ENSG00000175643
6  ENSG00000106367 NA AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1174 ENSG00000106367
7  ENSG00000171848 NA RRM2 ribonucleotide reductase M2 6241 ENSG00000171848
8  ENSG00000094804 NA CDC6 cell division cycle 6 homolog (S. cerevisiae) 990 ENSG00000094804
9  ENSG00000127564 NA PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 9088 ENSG00000127564
10  ENSG00000170312 NA CDK1 cyclin-dependent kinase 1 983 ENSG00000170312
11  ENSG00000106462 NA EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 ENSG00000106462


Database:Transcription Target       Name:hsa_V$E2F4DP1_01       ID:DB_ID:2233
C=236; O=11; E=0.49; R=22.34; rawP=2.97e-12; adjP=3.27e-11
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198826 NA ARHGAP11A Rho GTPase activating protein 11A 9824 ENSG00000198826
2  ENSG00000166803 NA KIAA0101 KIAA0101 9768 ENSG00000166803
3  ENSG00000100479 NA POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 5427 ENSG00000100479
4  ENSG00000101412 NA E2F1 E2F transcription factor 1 1869 ENSG00000101412
5  ENSG00000175643 NA RMI2 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 116028 ENSG00000175643
6  ENSG00000106367 NA AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1174 ENSG00000106367
7  ENSG00000171848 NA RRM2 ribonucleotide reductase M2 6241 ENSG00000171848
8  ENSG00000094804 NA CDC6 cell division cycle 6 homolog (S. cerevisiae) 990 ENSG00000094804
9  ENSG00000127564 NA PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 9088 ENSG00000127564
10  ENSG00000170312 NA CDK1 cyclin-dependent kinase 1 983 ENSG00000170312
11  ENSG00000106462 NA EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 ENSG00000106462


Database:Transcription Target       Name:hsa_V$E2F_Q6_01       ID:DB_ID:2297
C=239; O=11; E=0.50; R=22.05; rawP=3.40e-12; adjP=3.37e-11
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000093009 NA CDC45 cell division cycle 45 homolog (S. cerevisiae) 8318 ENSG00000093009
2  ENSG00000198826 NA ARHGAP11A Rho GTPase activating protein 11A 9824 ENSG00000198826
3  ENSG00000166803 NA KIAA0101 KIAA0101 9768 ENSG00000166803
4  ENSG00000100479 NA POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 5427 ENSG00000100479
5  ENSG00000051180 NA RAD51 RAD51 homolog (S. cerevisiae) 5888 ENSG00000051180
6  ENSG00000101412 NA E2F1 E2F transcription factor 1 1869 ENSG00000101412
7  ENSG00000175643 NA RMI2 RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae) 116028 ENSG00000175643
8  ENSG00000171848 NA RRM2 ribonucleotide reductase M2 6241 ENSG00000171848
9  ENSG00000094804 NA CDC6 cell division cycle 6 homolog (S. cerevisiae) 990 ENSG00000094804
10  ENSG00000127564 NA PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 9088 ENSG00000127564
11  ENSG00000106462 NA EZH2 enhancer of zeste homolog 2 (Drosophila) 2146 ENSG00000106462




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).